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Four hundred dollars a day, every day. For that amount of money, Adriana was willing to go through any kind of medical trial. The trial was supposed to be secret and the advertisement had been vague but she had flirted with the attendant at the labs to get some extra information. Apparently, it was something to do with a sustained reaction to something, like the substitute astronauts lying in bed for months on end. Even the attendant didn't know anything more than that. Adriana only hoped that nothing too bad would happen to her; those test subjects got quite a few medical problems afterwards. Still, she really needed the money.

Adriana was a vixen, just under five and a half feet tall with all the normal vixen bits: pointed ears, a large tail and a spade between her legs. She had a lot of fun with the last one although she didn't have anyone to share it with now. When she heard about this trial, and the specification for people overage, she'd jumped at the chance. Now she was standing outside the main building of Watcher Laboratories: a commanding edifice on the outside of the city. Adriana had been through three security checkpoints already to just get to the front door; this place was locked up tighter than the proverbial Fort Knox. Other buildings were scattered around the complex, each a different size, although none could be called small.

Showing the temporary ID badge to yet another guard at the door, the vixen entered the lobby. It was nicely furnished. The mosaic floor was scattered with comfortable looking chairs and couches and soft music was playing from somewhere in the ceiling. There was no receptionist desk but before long a mouse in a lab coat scurried over.

"May I help you, miss? What is your name? Do you have business here?" he said. Before Adriana could say anything in reply, he lifted a small scanner and with a beep, read the barcode on her ID. "Ah," he said, checking a small tablet. "One of the trials, yes?"

This time he waited for an answer. "Yes," Adriana said, a little annoyed. "The one that pays four hundred dollars a day for the duration of the trial." She stressed the amount slightly; it wouldn't do to get a lower paying one.

"Of course," the mouse said. He tapped the tablet several times. "I have to explain several conditions to you and then you sign here. Only sign if you understand everything I say." He cleared his throat and then spoke in a quick monotone, the speech obviously rehearsed many times. "By signing the contract before you, you agree to participate in a Watcher Laboratories clinical trial researching the average person's body. This trial is only available to those of adult age. This trial includes a compensatory wage of four hundred dollars a day to recompense any material loss suffered during the time spent away from work and to make participation in the trial more appealing. You will be on premises for the duration of the trial. Money will only be paid at the conclusion of the trial. An early exit must be agreed upon in advance and will result in all wage earnings being forfeited. Do you understand and agree to all of these terms?"

"Yes," said Adriana slowly. She thought she had caught all of the spiel from the mouse and she had no plans of leaving the trial early. Who would, when the money would be lost? Pressing a paw pad to the tablet, she signed her signature quickly before handing it back. "Are we starting right away?"

"Of course," said the mouse. "Follow me."

Leading the vixen to an elevator, he punched a code into a panel and the doors opened. Inside it was rather unusual; there were no floor buttons but another keypad. The guide input another code here and the elevator began to smoothly descend. There was no sign or lights to indicate the floor and Adriana was soon surprised at the time they spent going down. "How many underground floors does this place have?" she wondered aloud.

"A lot," the mouse said, checking his watch impatiently. " I don't know exactly how many. The lower ones are usually R&D and secret. I know that there are a lot of regulations when building up so the people in charge decided to build down instead. A lot more secure this way too."

The elevator eventually stopped, the doors dinging open to show an austere hallway lit with fluorescent lights. It was all white tile and plaster, with closed white doors dotting the hallway here and there. The guide took Adriana down the hall, passing a dozen doors. Adriana quietly marvelled at the extent of the laboratory's underground complex. This was only one floor of many and it seemed huge!

After a couple of twists and turns, they stopped at a door. The hall continued still further and Adriana craned her neck, trying to see as much as she could. There were a lot of medical and pharmaceutical smells on the air and a couple of doctors were walking between doors, wearing lab coats and holding sheafs of paper, clipboards or weird equipment in their arms, the purpose of which she couldn't guess at. "Please do not block the hall," the mouse said, holding open the door and tapping his foot impatiently.

The hustle and bustle of the underground lab was distracting Adriana but she tore her eyes away to enter the room the guide was ushering her into. It was small and sparsely furnished: a preparation room of some sort. It contained a bed, a chair, a table and a wall of cupboards. "Someone will be with you shortly," the mouse said and then left, shutting the door behind him. Weirdly, Adriana heard the lock click as the door closed.

Frowning, she got up and tried the handle. Sure enough, it didn't turn. There was no lock or keyhole on this side of the door. Assuming it had something to do with the security of the lab and trying not to think about being locked in a small room deep underground, Adriana sat on the bed. It was only a couple of minutes later when the door reopened, one of the doctors from the hall stepping briskly into the room and shutting the door behind him. A raccoon, he was holding a clipboard in one hand and a small case in the other. The glasses on his nose had slid down a little too far but the doctor seemed not to have noticed.

"Hello," he said, smiling. "You are Adriana, yes? Here for trial PAD001?"

Adriana glanced down at a slip of paper from her pocket with the date and details of her appointment. "Um...yes, that's the one."

The doctor put the case down on the table and flipped through some of the papers on the clipboard. "You had your last physical a month ago?"

Adriana nodded. The doctor asked several more questions, moving through the papers on the clipboard until at last he seemed satisfied. "All righty then, we can start. There are other people in this trial but due to the nature of the test, we can't give you any information about it beforehand. You already agreed to all of this previously in the contract you signed. I'm here to prepare you for entry into the trial."

From the case, he pulled out a paper gown and handed it over to Adriana, turning around as she quickly changed. The doctor placed her clothes in a cupboard over on the wall and then directed the vixen to the bed, pulling an IV bag from the case. "Lay down please and hold out your arm." The doctor carefully shaved a small patch of fur from Adriana's forearm. "Can you handle a needle?" the doctor asked. In truth, Adriana had hated needles ever since she was small but she nodded anyway. She had to look away as the doctor inserted the needle into her vein and jumped as it pierced her skin but was able to stop from reacting any more.

Almost immediately, Adriana felt weak and woozy, falling back onto her pillows as the drug in the IV flowed into her bloodstream. It didn't knock her out completely but it made everything hazy. She tried to lift an arm; it trembled and lifted about a centimetre from the covers before dropping back down. The doctor sighed, taking off his glasses and rubbing his face and mussing up his fur. He got up and walked over to the cupboard where he had stored Adriana's possessions.

While she watched, he picked up her clothes and threw them into the bin in the corner. "Hey!" Adriana tried to shout. Instead, all that came out was a slurred grunt and drool dripped from her muzzle onto the paper gown. The doctor turned to her but didn't talk or acknowledge what he had done. Instead, he took a firm grip on the top of the gown and yanked. The flimsy garment tore easily and after a couple more tugs, it was gone, leaving Adriana completely naked before the doctor. He looked down on her body while Adriana grunted slurred words.

To her horror, the doctor opened the door to the hallway. She was being exposed to everyone! "Some help in here," the doctor said, waving two more people into the room. They too positions at either side of her head and began to push the bed, laughing at her protests, not that they could be understood. Adriana and her bed were wheeled out into the hall, the doctor staying behind in the room. The two workers moving Adriana were not as professional away from his sight and supervision. The one on the left reached down to give her breasts a rough squeeze, laughing off the furious expression on her face. Oh, if only she could move! She'd tear this pervert attendant a new one!

Two big double doors banged open as Adriana's bed was wheeled through into the largest room she'd yet seen in the underground complex. It was low ceilinged but the walls stretched out beyond her line of sight. There were lines of beds on each wall and doctors and technicians milling around. Adriana didn't really have a clear view, being unable to turn her head to look around but she caught glimpses of other furs in beds though at the speed she was being wheeled, she couldn't see what those around them were doing. The speed helped her smell more though; there were more people in the room than she could even distinguish, the thick, cloying odour of medicine and sterile things overlaying everything.

Adriana was placed at the very end of one of the lines, next to the clean white wall in a corner. The movers left, one giving her nipple a sharp pinch as he walked away. The vixen could do no more than blink angrily and continue drooling. Almost as soon as the two men were gone, two people in lab coats came over: one a female panther and the other a bull.

"Female canine, optimal health and a prime candidate for the trial, Megan," the bull said, reading from a tablet. "Agreed to the contract and everything. And the investigator revealed no external connections of significance, of course."

"Excellent," Megan replied. "I'll get her prepped now."

The bull moved away and Megan wheeled a tray over. She didn't bother speaking to Adriana but grinned furtively and hefted her breasts, feeling them up rather more gently than the attendants before. Taking it from the tray, she attached a flat panel, about the size of a thumb, to the underside of Adriana's breast. Adriana whined as she felt the odd sensation of the fur beneath the panel dissolving and then a glue sealing it to her skin. It was only after a lead was attached to it that Adriana realised it was an electrode of some sort. Megan tugged on the lead firmly but it didn't budge, showing that it was well attached to Adriana for now.

Another panel joined the first on the underside of her breast, then another two on top with one final one on her nipple. The one on her nipple burned a little as it bound itself to her sensitive flesh. Another tug showed that it was as irremovable as the others. The same number was put on her other breast, in the same places and with the same tugs and leads. Then the doctor started on the rest of her body: they went on her feet, neck, face, neck, ears and a dozen other places, always placed slowly and methodically so that they adhered to her skin properly.

Adriana was in silent and impotent fits. Her beautiful coat was being ruined; there would be a bald patch wherever one of the panels had been attached and it would take weeks for the fur to regrow, if it ever did. But there was nothing she could do to prevent the panther from continuing; weak twitches, glares and slurred sounds did nothing to help. Her efforts weren't even acknowledged, not until the very end of the procedure.

It was at that point that Megan moved to Adriana's head, looking down directly into her eyes. She spoke quietly, so her words wouldn't carry "I never understand how you people could be so stupid. I mean, can you even read? It's lucky that this isn't really a cognitive trial 'cause the labs would be really scraping the bottom of the barrel if that was the case. Did you even look at your contract? Notice how it didn't specify an end date? The only people allowed into this trial are the ones that no one would miss on the outside. Your parents will be informed of something, a work opportunity overseas or an injury but the truth is you're going to spend a long time here on this bed."

The panther grinned evilly. "But you won't be bored. This trial is called PAD. That stands for Persistent Arousal and Denial according to the sheet. We're going to make you the horniest you've ever been in your life but never let you cum and see how it affects you. Should be quite useful for some of the other divisions. It helps that this will be incredibly hot to watch."

Adriana's eyes widened and filled with tears as she listened to the panther's words. She clearly saw the last item that Megan held in front of her. It was a double dildo, a long cock with a fat knot on the bottom next to an equally wide butt plug. It was already dripping with lube and made of a clinical white silicon. From the distance that it was being held in front of her face, Adriana could even see the electrodes placed all along its length, evenly spaced from the tip to base. Once it was inside her, there would be no shortage of ways for them to torment her.

The pantheress roughly pushed Adriana's thighs apart, setting the tip of the cock against her spade. She made sure to look at Adriana's face as she slowly pushed, letting the vixen feel herself getting spread wide. A little way down the length, she felt the plug bump against her tailhole. She clenched her muscles as much as she could but whatever drug they had given her weakened her there too and they wouldn't respond. The fat plug sunk into her without much trouble and soon Megan was grinding the knot of the dildo roughly against her spade.

Panting, groaning and drooling were the only things the vixen could do as the knot was forced past her entrance with an audible pop, the plug in her ass seating itself inside her as well. Never in her life had she felt so full, stuffed in her pussy and ass with no more space left. The toys felt almost too big and were uncomfortable, the knot especially stretching her walls. Despite being a canine and having a string of lovers, the only knot Adriana had ever taken was a small one on a toy of hers back in her now empty apartment.

"Aw," Megan teased, smirking and pressing down on the vixen's belly as though trying to find the shape of the dildo inside her. "Is it too big? You'll get used to it, at least until I change it for a bigger one later on."

She placed another half dozen electrodes right on Adriana's sex, each of the lips of her spade getting two and one right on her clit, the panther's insensitive touch making Adriana squirm as she manipulated the tender bud. Then, she picked up something that made Adriana squirm more than anything else so far: the tube of a catheter. It was already lubed and Megan wasted no time inserting it into Adriana's urethra. The sensation was completely new to the vixen and very uncomfortable. Megan was smiling, clearly enjoying her patient's discomfort as she pushed the tube into her. The panther then inflated the small balloon on the end of the catheter to keep it well secured with Adriana. As soon as she was done, the panther went right back to grinning predatorily. "All done sir," she called out. "Patient is ready to begin."

The bull reappeared in Adriana's field of vision. "Excellent. There's a couple more over here that are almost done and then we can get started. Are they connected to the node?"

The rest of the conversation was lost to Adriana as they walked away, the grunts and moans of the other hapless patients drowning out the voices of the doctors. She was left to stare up at the roof, the girth inside her still uncomfortable as she clenched down on it weakly, trying to push it out. Slowly, the other sounds quieted down until the bull's voice filled the room again. "Starting trial PAD001 with subjects one through fifty. Current duration is undefined; we'll see how it goes before halting the experiment. Beginning stimulation in three, two, one..."

Adriana squeezed her eyes shut, waiting for something to happen. She wasn't disappointed. Warmth and an electric energy suddenly burgeoned wherever the electrodes were placed on her skin. It wasn't a distinct feeling that she could pin down, other than it just felt inexplicably good. She knew what it was, what was happening but that didn't stop her nipples from hardening and a breathy moan escaping her. The electrodes were placed on every possible erogenous zone she possessed and even with the hit-and-miss placement, it was extremely effective. The vixen was getting turned on faster than she ever had been before, faster than she even thought possible

It took only a few minutes for Adriana to stop trying to resist the feelings, instead succumbing to the need now filling her body. She wanted more but the sensations frustratingly stayed away from her sex, playing over the rest of her body instead. Perhaps she was imagining it but it felt like someone was stroking over her breasts and nipples, making her weakly push into the feeling. When she looked, there was no one there. It was like the most intense foreplay session she had ever been in. Please, she begged in her mind. Do something else!

Her wish was answered. Her sex, already wet, clenched weakly around the toy as a pulsing vibration ran through it, the feeling not at all distinct and shockingly powerful. After the vibration, there was a current that made her sensitive walls tingle and clench hard around its shape, much harder than Adriana could do herself. She gasped at the sudden surge of pleasure then yelped quietly, the loudest sound she was capable of making. The pad over her clit had come to life. Like the other electrodes, it gave a feeling of pleasure but this was so much more than anywhere else. It was almost too intense, Adriana jerking weakly for a moment to try and lessen it. The feeling continued and she quickly lost the oversensitivity.

It was unlike anything that the vixen had ever experienced. She had never been particularly slow to cum but this was insane. Already her sex was tingling with the nearness of an orgasm and barely any time had passed, mere moments since the beginning of the trial. Her breathing grew faster and shallower until she was holding her breath, hips twitching upwards slightly. She didn't breathe for a full thirty seconds before letting the air out explosively. The orgasm that she had been heading for was just out of reach. She couldn't feel any measurable decrease in the feelings and sensations assaulting her but although they were enough to get Adriana to the edge, she couldn't push herself over.

The longer she hung on edge of climax, the stronger all of the stimulation seemed to become. The fur around her sex and on her thighs became matted with her arousal, the moisture actually helping the currents travel through her. Around the vixen, the other patients began to vocalise again. Moans, yelps, and needy whimpers filled the air and in moments Adriana began to add to them herself. She tried to lift her hands to her sex, to give her clit the tiniest bit of attention it needed or to grind the dildo a little harder against her g-spot but it was no use. Her limbs did no more now than they had before, only twitching weakly on the sheets.

There was a gurgling sound and Adriana howled as loudly as she could as lukewarm liquid filled her ass, pumped into her through the plug seated there. For a moment, she thought the slightly uncomfortable sensation might be enough to cause her to orgasm, but it didn't. The liquid filled her until she groaned before draining away as suddenly as it had appeared. It was then that the part of Adriana's mind not overpowered with her need filled with dread. With the IV lines, catheter and these enemas, there was no limit to the time that she could spend here on this bed, mercilessly stimulated. She could stay here for the rest of her life, exactly as she was now, on the cusp of an orgasm that would never come.

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Megan sighed, pressing the elevator button repeatedly in time to the beat of the music in her earphones. It was the graveyard shift again, one that was being given to her more and more often lately. She hadn't been able to see her friends or family for more than a fortnight already. And it wasn't even anything good; she was just tending to the running experiments.

She pushed the cart out of the elevator, the contents rattling a little as they travelled over the bump in the floor. The cramped hallways made manoeuvring a little more difficult but the panther was well practised by now. With a swipe of the key card at her belt, she opened the first door, being sure to keep it open with her foot as she wheeled the cart into the room. The smell inside was thick and cloying, a mixture of sex and disinfectant. Inside there was an anthro wolf in a straitjacket, her breasts and spade visible through openings in the material. A chain linked to a collar and the far wall kept her from stepping too far out into the room. The was a thick gag muzzling her but her eyes were expressive enough as she tried to come towards Megan. The chain snapped taught but the wolf moaned through the muzzle and gag, thrusting towards the panther with her hips.

Megan's face twisted into an unhappy expression. She hated working with these horny subjects they were barely more than animals. This one was stuck in a permanent heat and she certainly smelled it. The wolf had a clear plastic shield over her wet spade, similar to a chastity belt. The story of this patient was written down somewhere or other and Megan had read it at some point. Apparently, she'd been in another facility and reacted oddly to a heat-inducer. They'd brought her here to study but, of course, she'd been left to Megan's care, on top of everything else she had to do.

She set about changing the food and water that the wolf had access to then, her least favourite part, removed the chastity shield. The wolf moaned loudly and tried to grind against her hand but Megan pulled away before she could, holding the plastic out at arm's length. It was literally dripping with the wolf's arousal, a result of being pressed tightly against her sex. Megan dropped it into a bin on the cart and pulled out a new one, holding out the triangle of straps.

At the sight of her approaching, the wolf's eyes widened and she pushed herself into the corner, away from the approaching Megan. "Come on," Megan told her grumpily. "This is happening no matter what."

With her arms bound tightly in the straitjacket, there wasn't much that the wolf could do. Plus, she was in a corner. Megan knelt on the wolf's thighs to stop her squirming and mashed the plastic shield against her spade. The patient shuddered, going limp as she got the first bit of stimulation to that part of her in days. It gave Megan enough time to wrap two of straps around the wolf's waist and feed the third between her legs. By the time the wolf started to move, the chastity device was back in place.

The wolf howled muffled, a sob clearly audible through the gag. She threw herself onto the ground, lying on her stomach and futilely grinding her covered sex against the floor. Megan left her like that, heat-crazed and trying to masturbate without the use of her arms.

The door clicked closed behind the cart, the panel light flashing red as it sealed. One patient down, another dozen to go. The next room she opened was quite a bit larger than the cell the wolf had been in. This one held an ongoing experiment. Megan actually smiled as she remembered the day more than four years ago; she had helped set this one up, getting the participants ready.

There were about fifty of them, all stuck in beds next to blocks of machines. For the last four years, they been fed through IVs and scrubbed clean from the inside, all the while kept immobile and on the edge of orgasm. The trial was supposed to test the effects of the now-old stimpatches, both short term and long term. Not that Megan would still be here by that time. Still, this was her favourite time of her rounds. Not all of these patients were under the panther's care so she went around to the beds that were her duty.

It was a sticky and messy job. The first patient was a male raccoon and the first thing Megan did was run a cloth up and down his shaft. His cock was sticking up straight up, a constant, slow stream of precum dripping down his length. Even since the last person had come to clean him a couple of hours ago, the fur of his thighs and stomach were sticky. She wiped him clean with the damp cloth then lifted his cock in her hands. He might have always been well-endowed or maybe it was a side effect of the constant edging but his cock now wouldn't have looked out of place on a stallion, a considerable feat considering their difference in size. She could feel his heartbeat clearly through the hot flesh and it leapt in her hands, twitching.

She looked at the raccoon's head. There was a light muzzle to keep his mouth closed and prevent drooling but apart from that, he was unbound. The paralysis drugs made any restraints unnecessary. What turned Megan off was the glazed eyes staring into space. He didn't react to her gentle stroking of his cock except to thrust slightly into her grip. She couldn't see a person behind those eyes anymore and that took all of the fun out of it.

The IV was replaced and the machines checked over. Nothing was out of the ordinary so she moved on to the next patient, then the next and the next. All had the same blank-eyed stare. The females were harder to clean. Their juices flowed around the dildos embedded within almost constantly, forcing Megan to keep cloths underneath their crotches at all times to catch their excess arousal. Still, it wasn't so bad with the music blasting away in her ears, her body mechanically following the routine she had made over the years.

Then she got to her last charge. She always saved this one for last. There were only a couple in the room that showed any signs of life when someone came near and this was one of them. She was a wolf, named Adriana according to her chart and her eyes flicked to Megan when she stood by her head. "Hello," Megan crooned, stroking the wolf's head. "Ready for the next one?"

The wolf gurgled weakly and Megan smirked. When the trial had started, she had promised this wolf special attention and she had made sure she got it. She pulled something from the cart and held it in front of the wolf's eyes, making sure she got a good look. It was a massive dildo with two prongs, one vaguely canine and the other shorter and fatter. The knot on the canine shaft was easily larger than a softball and the width of the anal shaft was only a little less. Megan had been switching out the wolf's dildo every now and then for larger and larger models, making sure to keep stretching her out and keep it interesting. After all, Megan reasoned, it's not lie anyone else pays any attention to her.

Setting the new one down, Megan slowly tugged on the old dildo, slowly pulling it from the wolf. Her spade deformed and bulged as the knot popped out then the rest of the dildo followed, along with a wave of the juices the knot had been keeping locked inside her pussy. Her holes gaped open for a few moments and Megan could see the rhythmic clenching of her inner muscles as the was stimulated by the machines. The constant arousal had swollen her spade a lot and her clit looked twice as big as it should, throbbing outside the protection of its little hood and still covered in the stimpatch. The cloth beneath the wolf's crotch was already soaked through so Megan picked up the cloth and used it to lube up the newer, larger dildo, especially the anal part. The bitch was already so wet that the other shaft would slide right in.

"Ready?" Megan said, poising the tip of the massive shaft at the wolf's spade. "Here we...go."

She pushed firmly and the dildo began to enter the helpless wolf. There was a bit more resistance than Megan expected; even with the large dildo before, she was a bit tight. This new toy would be sure to stretch her out. She wouldn't be fit for anything by stallions after this though Megan doubted she would ever leave the room. The anal shaft pressed against Adriana's tailhole and then pushed past that, her own juices easing the entry considerably. Megan smiled wider as the wolf made little huffing noises, no doubt trying to orgasm from the sensation of being filled up more than ever before, again. Considering how often it had happened in the past, Megan thought she would have learnt by now that it was impossible.

The vaginal and anal parts were deeply seated now, only the knot remaining outside the wolf's body. Megan ground it against the wolf's swollen spade, playing with her prey, making the patient hold her breath in worried anticipation. Then, she put her weight behind. The wolf groaned as her spade was mashed down hard and then slowly, very slowly, began to spread around the knot. With an audible pop, her lips strained around it and then swallowed it, seating it within her walls. Adriana shuddered, her sex and ass trying to milk the artificial lengths within and give her the extra bit of sensation needed to cum. But, of course, that didn't happen.

Megan laughed and patted the wolf's cheek. "Wait until next time," she whispered. "Maybe I'll give you one with spikes or something on the shaft; give you something different to feel." Still laughing, she wiped her hands on the wolf's face, matting her fur down with her own arousal. Then, taking the trolley, she left the room, feeling the wolf's eyes on her back as she howled quietly.

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The security screens were the only source of light in the room and only the silhouettes of the two people within it could be seen. They were looking intently at the screens which showed the feeds from the Level 36 testing rooms.

"You know, I think that nurse, Megan, is no longer a good fit here. She seems to have lost her objectivity and her habit of interacting with the subjects has gotten out of hand."

"I agree. Perhaps we should shift her to a less...independent role. At another facility, perhaps."

"Hasn't the hospital experiment out west just transferred a patient here? The transfer team will be returning in a few days, after their leave is complete."

"Excellent. You make the arrangements; send Megan out there. Oh, and sign her up for a couple of treatments. She should be cured of this sexual sadism."

"Of course. It wouldn't do to waste such a perfect subject."