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Day One

The future wasn’t what they’d been promised, Mary thought, as she read the latest blog updates online. Hell, it wasn’t what anyone had been promised. It seemed like all of the negative predictions had come true, while none of the positive ones had. No space travel, no flying cars, but a total corporate takeover of the country, the blog went on, detailing all the ways things had deteriorated.

Mary sighed as she looked out the window. It was another cold morning, and she couldn’t quite tell if the fog outside was actually fog or just pollution as usual. It had gotten worse since they repealed all the environmental protection laws. Much worse. Some days she couldn’t even go outside without coughing her lungs out.

At least her home had an air purifier. It was, however, a subscription service like everything else, and she and her partner Kaiden were rapidly running out of money with the prices constantly going up despite service getting worse. Their subscription-based self-driving car had already driven itself back to the dealer because they couldn’t afford it. They’d cut their television subscription and the TV itself had been taken away, as was the way of things after all the consumer protection laws had been repealed too.

She slowly sipped her coffee. It tasted decent enough, and she really didn’t want to end that subscription. Mary, modest as she was, felt like she needed at least some joy in life, but in the end, the coffee subscription was still an extraneous luxury. The air purifier was not.

It wasn’t that they couldn’t technically afford it, but Kaiden had been unemployed for about a month now after his employer had fired him for not smiling enough. His role had been replaced by a robot with a permanent smile plastered onto its face, always happy and polite and utterly useless at its role in customer service, but the boss didn’t really care about performance. In fact, he was rather happy that customers gave up their attempts to complain or get refunds due to sheer frustration of dealing with yet another AI support. All that mattered was that their new mechanical “service agent” smiled happily as they did so.

Yeah, employee protection laws had been cut, too. The blog she was starting to struggle to confront the reality of reminded her, too. But really, that was no surprise; things had been headed that way for a while, along with the burgeoning national debt. Someone had promised to fix it, and they’d elected him, only to find out that while he happily cut legal protections to save money, the increased tax cuts for the extremely wealthy more than compensated, and the debt kept climbing, necessitating more and more laws and regulations being repealed, which meant worse quality of life for just about everyone except the ultra-rich. By this point, it was obvious, and articles like the one that Mary was reading made it abundantly clear. But there was nothing they could really do about it except despair, as she was doing.

At least she still had her cat. Their cat, technically. She’d bought the little bugger before pets had become a subscription service too. Currently, that black ball of fur was curled up in her lap and purring happily, doing his best to keep her sane despite everything, and Mary truly did appreciate it. Of course, the cat – Mr. Whiskers – had been affected by the state of things too. Without any regulation, several brands of cat food had started adding something that wasn’t entirely safe for consumption, and he’d gotten sick. That had left him needing expensive medication that the vet told them would be necessary for the rest of his life, which put a further strain on their finances.

Mary, for her part, still had a job – which just barely managed to keep them both afloat, minus the car and television, now – but it wasn’t fair, Mary thought, and Kaiden usually agreed, for her to have to do everything, and on top of that, she was depressed. Oh, it was hard not to be, almost impossible. After all, all you only had to look out the window, and you’d have plenty of reasons for it. Though Mary realized that doomscrolling through blogs wasn’t helping, as much as she felt that she had to know every terrifying new update. She managed to close the browser.

They had, to the best of their abilities, tried to make their home a kind of sanctum, a reprieve from the increasingly depressing outside world to help Mary cope, but it had only been successful to a degree. And so, she was starting to feel burnt out, but still dutifully headed to work as she was obligated to by both society and the fact that they needed money for food and that damn purifier. But every quiet moment at home was spent ruminating about the misery of it all with Mr. Whiskers, which had put quite the damper on her formerly fantastic sex life with Kaiden.

Kaiden, with the muscular physique and broad shoulders that a healthier Mary had once been so fiercely attracted to, sat by his computer while Mary was doing her usual coping. He didn’t blame her for it, not one bit, and he was perilously close to falling into depression himself as he checked rejection email after rejection email. And those were the good outcomes; almost half of the jobs he applied for didn’t even bother sending one. He almost wanted to bring Mr. Whiskers over to make him feel better too, but right now, Mary needed his purring and warmth more.

He also really wanted to bend his curvy wife over the way he had used to and just fuck her senseless over and over until they were both too exhausted to even stay awake. He wanted to lift her up, pin her against the wall, to squeeze her perfect, milky-white and teardrop-shaped breasts, to suck on them, to eat her beautiful, delicious pussy. Just as they once had, and often. But things just weren’t conductive for that kind of revelry right now, he ruminated. One day, it’d get better again, right?

Rejected for barista. Rejected for office assistant. Rejected even for janitor. Kaiden buried his face in his hands and sighed. If things didn’t get better soon, they’d have to get rid of the cat, and that’d ruin Mary. Either that, or they’d get rid of the air purifier, and that’d ruin all three of them with how horrible the air quality had gotten. He started on his second coffee as he filled out more applications, sending them to every employer who had a job ad out, but his hopes of actually getting hired by any of them were fading with each passing day.

He, too, looked through the window at the rainy, foggy, bleak world outside. His eyes scanned along the horizon, from the manufacturing plants belching black smoke, to the pharmaceutical district. That was a place where he could’ve easily worked a few years ago before they automated everything and kicked out all human employees except upper management and a few doctors.

Doctors. Suddenly he remembered something that his equally unemployed friend had told him. Something about selling his body to science for experiments. That, he had said, paid well – robots didn’t make for good test subjects – but at the time, Kaiden had rejected the idea, considering it far too dangerous since he “knew” that he’d find a new job before the month was up. Now, it suddenly seemed like a far better idea.

Who was it that owned the building he just looked at again? There it was, in bold neon letters, visible even here, miles away. Genron. They were always working on new experimental treatments, and experimental treatments surely required test subjects. The sign suddenly seemed like a guiding star, in lieu of the ones now obscured by light and pollution. But a star could just as easily guide one towards salvation as it could damnation, and it certainly didn't care which one any given individual was led to.

There was a risk to it, certainly. But if both he and Mary somehow managed to sign up for it, they could at least suffer through whatever side effects occurred together, and it might just solve their money problems until he could land a more lasting gig. Hell, it might even solve her depression, if they had any planned treatments for that.

Slowly, he convinced himself that the idea was good. Maybe it wasn’t, but he was at the point where he couldn’t afford to entertain that thought, and so, he didn’t. Instead, he searched for Genron's website and clicked. He checked their available positions first in a last-ditch effort to avoid having to take the final, most drastic option, but as expected, that effort was in vain. They weren’t hiring anyone below managerial and scientist levels. And so, he navigated to a distinctly more threatening page; that for paid test subjects.

The trials were divided into four categories: low risk, medium risk, high risk, and extreme risk. A quick glance revealed the first category to be final tests of already tested drugs. The second was drugs that had already started human testing, but not extensively. The third, where the promised pay shot up significantly, were drugs that had only been tested on animals, and the last – very lucrative – were drugs that showed promise in vitro but had never been tested on full organisms. Typically, those would never be tested on humans, but it was a brave new world that Kaiden found himself in.

A little too risky, maybe, that last category. Sure, he and Mary were getting desperate, but they weren’t that desperate. “High risk” paid well enough that they could get their car back while he found a job, however long it’d take. The trials were all very long-term; a few years for each drug.

He looked at exactly what was on offer. An athletic supplement that was promised to improve strength and endurance. The side effects included unexpected physical changes, with a low likelihood of being deformative. That didn’t sound too bad. He pictured himself losing his hair, which had already been thinning, but with abnormally big muscles. At most he’d grow another finger or something, Kaiden reasoned. The other “negatives” sound exciting, like excessive libido.

There was an additional warning, written in a very tiny font, about how mixing any of the experimental medications or taking more than prescribed was not recommended. Kaiden seemed to remember something like that in the news; someone had done just that and… well, he’d never been seen again. But that wouldn’t be a problem for Mary and himself, he reasoned. They were responsible enough.

He called Mary over, and she came quickly, reluctantly placing Mr. Whiskers on the couch.

“Experimental drugs?” she asked, visibly confused by his plan. “So we’re going to be like, guinea pigs?”

“Well, yeah, but a lot of this stuff seems pretty harmless and if we both do one, we’ll easily have enough to make ends meet,” Kaiden explained. “See, there’s even a new antidepressant.”

The antidepressant, also in the high risk category, was described as having an extremely positive effect on bad moods. The risks listed included hypomanic states and mental fog_,_ but Mary figured that some excessive happiness and a little mental fog was well worth not feeling like yesterday’s unrefrigerated leftovers every morning.

She stared at the screen. It was clear enough that their current situation wasn’t sustainable, but she wasn’t sure how much she wanted to risk to make it better. High risk sounded menacing, but darkly, she wondered what other choice they had. It was either this, or they’d have to get rid of their beloved cat or the absolutely necessary air purifier, and that meant there wasn’t really a choice at all.

Besides, she tried to tell herself, if her depression was alleviated, there was a real chance of her managing to get a promotion at work too. She had been lagging, unable to do as much as she once had, purely due to a deep-set lack of motivation, owing to the fact that everything felt terrible. Yet, she had already seen what a good course of medication could do for their pet: Mr. Whiskers had gone from barely moving to playful and loving almost overnight. If it worked anything like that – the drugs did have the same manufacturer, after all – then their problems would be solved.

And, that very human and thus rationalizing part of her mind added, if things went poorly, what would they really lose that they wouldn’t have lost anyway? If they ended up severely disabled, there were still at least some safety nets in place for the worst cases.

“I guess we could do it. You on the muscle pills and me on the brain pills,” she suggested, fighting the dark urge to just give up and call it hopeless. “And then we’ll just see what happens until you get a job again.”

“Yeah. So, I’ll sign us up and hope for the best,” Kaiden replied. His fingers trembled a little as he typed in their details into the website. Unlike job applications, the process was simple; all it needed were names, addresses, and ID verification to make sure they were who they said they were. And, of course, two very long contracts for them to sign where they promised not to sue or otherwise damage the Genron brand, that they understood the risks and consented to taking them, and that their progress would be automatically monitored through equipment already present in their house.

Wait, what? “I consent to Genron using present electronics to monitor progress.” There it was, plain as day. Could they simply access anything with a camera or sensor just like that? Was everything they owned capable of spying on them?

No matter. They couldn’t do anything about that.

Much to their surprise, they quickly received a message informing them that they’d get their respective supplies of medicine today in just a few hours, Genron clearly eager to get the testing underway. Sure enough, just a few hours later, a stressed and harrowed-looking courier was knocking on their door with an enormous box full of the stuff, equally divided into bottles for them both.

Together, and without any hesitation bar for a few trepidant glances, Mary and Kaiden swallowed their first pills. They didn’t look like much beyond the usual white oval form. They were completely unmarked, felt somewhat chalky and tasted a little sweet. Nothing else. Neither did they experience any immediate effects. It was almost anticlimactic, in a way, though not necessarily negative. It was better than immediately dropping dead, at least.

But of course, many things happen inside the body that you aren’t aware of, and no sooner had the pills had begun to dissolve in their stomachs, than those changes were already starting to take place. As they slept that night, a myriad of half-researched chemicals worked in their bodies, subtly modifying some parts of their minds and bodies while drastically altering others.

Day Two

The next morning, Mary felt no different, but Kaiden felt great. He felt energetic to the point that he slammed down his morning coffee and immediately headed online to look for new jobs. The first payment for starting the trials didn’t hurt, either; in just another month, they could finally get their car back, and he’d be able to apply for all the jobs that required one, too.

That wasn’t all. He also felt horny. Extremely horny, though still able to focus enough to fill out about twelve job applications and send them in, despite his cock threatening to tear through his pants, and feeling bigger and firmer than it ever had before. If this was what the side effects were going to be, he mused, he could get used to them.

And if they feel this good, why not take a little more, whispered a voice of primitive urge and instinct at the back of his head. With double the dose you could really get some gains, and once Mary’s up for it you could fuck her brains out too.

Kaiden shook his head. He knew he shouldn’t. The drug was experimental, after all, and there was no guarantee that it’d be the good effects that compounded as opposed to something bad that he hadn’t noticed yet. He might end up having a heart attack or worse.

Kinda unlikely though. Chances are you’d just get more muscular and motivated, and maybe have to jack off more often until Mary’s recovered.

It seemed almost reasonable, if in a very stupid way. It was the same kind of reasoning that always led to bad decisions; drinking or smoking too much, pushing yourself just a little too hard during a workout, or sticking your cock in inadvisable places. Kaiden knew it well; he’d been a teenage boy once, long ago. But he wasn’t one anymore, he reasoned, so he could think about this logically.

So where did logic bring him? Kaiden squeezed his cock and nearly moaned at how good it felt. He felt a little bigger than before, or maybe just harder. Would the pills make his cock grow too? That thought certainly felt exciting. He could grow muscle normally, but a bigger cock was such a powerful lure for almost any man. No, he was imagining it. If the pill caused cock growth, that’s how they’d market it, wouldn’t they? They’d make billions off just that effect.

He glanced at the pills in his hand. There had been that little warning about taking too much. No, he wasn’t that foolish. Was he?

Mary, meanwhile, was starting to feel a little strange. There was nothing as obvious as it was for Kaiden, but she felt floaty. A little bit dazed, as if she was somehow insulated from the outside world. Not a bad feeling, just somewhat introspective, perhaps. The kind of mood where she wanted to curl up under a thick blanket and just be cozy, which she thankfully had time for, now. Genron had arranged it so that she wouldn’t have to work while undergoing the trials. Her employer had protested, but the pharmaceutical juggernaut had entirely too much sway. She didn’t know what exactly they’d said, but she imagined it was probably about taking them to court if they argued.

But she felt okay. Maybe even good. Maybe everything wasn’t quite as hopeless as it had seemed, though it was a little difficult to focus her mind on anything specific. Ah, it was probably nothing to worry about, she thought. She’d surely regain her ability to focus once the treatment was over, Mary concluded as she called Mr. Whiskers over to cuddle with her, marveling at just how soft the cat felt. Her skin was definitely more sensitive, which wasn’t a bad thing.

Kaiden swallowed another pill in the other room. Nothing ventured, nothing gained, and all that. If it did result in something bad happening, he could just go back to the base dose and enjoy those effects, right?

By the evening, he was feeling twice as strong as he ever had before. He wasn’t imagining it; the weights he had been lifting felt incredibly light now, and if it hadn’t been for the smog still lingering outside, he felt like he could’ve effortlessly gone for a ten-mile jog. But with no outlet for that sudden burst of vigor, it all ended up being channeled the same way it often did for men: directly to his cock

He was beyond horny. Maybe, he hoped, Mary would’ve recovered enough to let him fuck her quickly. It had been a while, and thanks to the medicine his balls felt like they were about to burst if he didn’t get to empty them. He really felt like someone had shaved fifteen years off his age and he was back to feeling like a teenager, his hormones raging and cock aching for attention.

“Kaiden, I’m just not in the mood,” she sighed, curling the blankets around herself more firmly, as he tried to cuddle up with her. “I mean, I feel a little better but I’m just not horny, you know?”

She sounded almost sad about it. Though frustrated, Kaiden accepted it; he probably wouldn’t have wanted to fuck if he was depressed either.

“I could try doubling my dose and seeing how that goes,” Mary offered. “I mean, at least it can’t do any harm, right?”

“Guess it can’t. Mine just has me so goddamn horny,” Kaiden sighed, already resigned to another night with just his hand, or maybe the one sleeve toy he owned. But even as he turned around to leave Mary alone for now, a new, devious thought occurred. He could mix a little of his medicine into hers. If it made him this horny, surely it’d make her horny too, right?

And there it was, that inner conflict between immediate gratification and logical long-term consideration of consequences once again, as if it had never left, but this time, Kaiden restrained himself. He’d at least wait to see how Mary’s higher dose worked, first. She was his wife, after all, and it wasn’t really reasonable to sneakily get her horny just so he could get his dick wet again.

Was it? Maybe it was. Just this once. He’d just do it once to see what’d happen, and then never again. It couldn’t be that bad for her, and maybe it’d even cheer her up.

Day Three

The second morning after they had started the pills, Mary woke up feeling even more dazed than before. She had doubled her dose, and this time, the effects were immediate. She still didn’t feel horny, but she did feel good and soft. A morning inspection in the mirror revealed that she had put on a few more pounds in all the right places, and she couldn’t help but admire the result for a moment. Mary hadn’t felt this good in ages, and that realization had her feeling warm and fuzzy all over.

There was still that mental fog, continuing to make it hard to focus, or even think now, with the higher dose. That was probably normal, wasn’t it? Her life felt like it had quickly become a series of questions with obvious answers, yet ones that she somehow wasn’t sure about. She squeezed one of her generous breasts, marveling at how it squished beneath her fingers in the mirror. It was as if she was drunk or intoxicated, but that couldn’t be. The stuff she was on was medicine, not drugs, Mary argued internally, her flawed arguments quickly becoming truth in her increasingly uncritical mind.

Mary went to give Mr. Whiskers his medicine. What a family we are, everyone on different drugs just to cope with the world, she thought, measuring out the two pills required and mixing them into the cat’s food. But at least it was working; the world was quickly lightening up and seeming like a happier place. If only it wasn’t for the damn mental fogginess, she thought. She almost gave Mr. Whiskers three pills instead of two, thankfully just barely catching herself, and meant to place the third back in the bottle.

But by then, everything was a blur. A nice blur. She didn’t mind. She measured out her own medicine. The bottle looked fuller than before, but she reasoned she’d just forgotten the exact amounts.

She took her pills as before, and once she’d swallowed two, she realized that there was one left in her hand. She must had only taken one, right? Good thing she looked, she sighed with relief, or she would’ve missed half of her dose. And so, she swallowed that third pill too; they all looked identical, owing to the fact that all experimental drugs were being produced with no markings by the same machines. Of course, what she didn’t know was that she had just taken not only her own medicine, but also a dose of Kaiden’s – which he had replaced every other pill of hers with – and the cat’s.

Mary then got to work, as much as she wanted to just be lazy all morning.

As she worked, though, doing the dishes – having paid time off her real job was a blessing, and exactly what she needed – she started to notice something strange. It was just a soft glowing feeling somewhere in her lower belly at first, but it quickly grew from there. She felt invigorated, like she’d had multiple cups of coffee in a row, but that wasn’t all of it. Quickly, she began to feel horny, too. Horny like she hadn’t been in months, enough to leave her panties clinging wetly to her folds, and her stiff clit rubbing against the soft, damp fabric.

Mary felt fuzzy. Not just her mind, but her body too. It was impossible to worry about anything in this state, but she had the notion that she’d mixed something up, and as she returned to look at just what bottle she had taken the pills from, she realized that she’d just poured half the bottle of the cat’s medicine into her own, and couldn’t tell any of them apart. She understood, on a base level, that this should’ve been a concerning development, but instead of panicking, she shrugged. Mr. Whiskers had enough of his own medication left, and they could afford more if it came to it. It probably wasn’t a big deal if she accidentally took some of his; certainly, she felt good.

Over the next few hours, though, she began to notice changes. At first, she thought she was dreaming as she noticed short, soft fuzz starting to grow all over her body, but it felt real, and even pinching herself didn’t help. Mary was, she realized, growing fur. Stranger yet, she liked it. A quick look in the mirror revealed that her pupils had narrowed. They weren’t entirely catlike yet, but distinctly more oval in shape than they had been.

At dinner, Kaiden proudly showed off his new muscles to Mary – who dressed in a baggy sweater to hide the fact that she was changing as best as she could – and she wolfed down her food, the physical changes leaving her absolutely ravenous, and as Kaiden handed her what she thought were her pills for the day – this was when she usually took them, right? – she didn’t even stop to question it, swallowing them down with a big glass of water and without thinking.

He certainly looked hot. Mary felt a little stirring of arousal as she watched Kaiden flex and pose – he looked so incredibly firm and strong – but they didn’t do much else that night either, not with Mary worried that Kaiden might not like her sudden cat-like features.

But she kept changing, and she liked it; the way her entire body felt so deeply sensual with ever longer black fur, especially. And the way her pussy tingled with the beginnings of a feline heat that she couldn’t possibly recognize. Mary found herself walking on her tippy toes, the position growing more comfortable than putting her heels down. And there was a strange kind of pressure just at the bottom of her spine. Yet it didn’t seem to go anywhere.

Mary had the idea of taking a few more pills just to push through these changes, and it seemed like a perfect reasonable – and deeply erotic – idea to her cloudy, increasingly instinct-driven and lust-inflamed mind. Maybe just one more so she could grow out her tail, but not knowing which pills were which, she’d have to take three just to make sure. And she did. Her muscles swelled almost immediately, not to the impressive girth of Kaiden’s, nor big enough that her hoodie couldn’t hide them, but strong enough to make her feel sexy.

As she eventually got ready for bed, there was a strange itch at the back of her mind. Some new desire, slowly growing along with her tail. She couldn’t recognize it yet, and she had to lay on her tail to keep it still, and in turn keep Kaiden from noticing that sensual new appendage. But sure enough, tonight would be when her body, overloaded with all three drugs, began to truly change in a drastic way.

Day Four

Mary woke up in the middle of the night, ravenous in an entirely different way. Her entire body was tingling with need, and not just that; her fur had grown long enough to be impossible not to notice, but she didn’t care, her pussy was burning for attention, and with a quiet meow that she didn’t even utter consciously, she licked her lips – finding that her face was slowly stretching outwards into a muzzle – and straddled Kaiden’s sleeping form.

The movement roused him, and he opened his eyes to see the dark outline of someone who he knew was his wife, but she looked very different. Her hips were wider, her breasts bigger, and of course, she seemed to still be in the process of transforming into a cat; her tail was almost fully grown and lashing side to side in excitement, and her eyes reflected just enough light to look bright yellow in the dark.

“M-Mary?” he stuttered. Though groggy from being so abruptly woken up, he wanted to ask what had happened to her, but in the end, he was fairly certain it was his fault for dosing her with so much of the experimental medicines.

She looked stunning, and better yet, she was finally horny again_,_ grinding her soaked lips against his thigh with graceful, feline motions while purring. That was a moment Kaiden certainly didn’t want to interrupt with unnecessary questions, and doubly so when her slender, furred fingers wrapped around his rapidly hardening cock.

“Fuck me,” she whispered, in a husky tone, and then wedged his glans against her dripping entrance. Kaiden couldn’t remember her ever being this needy, and so, cat or not, he was rock hard instantly, thrusting up on pure raw instinct to impale his beautiful feline wife on his cock. She yowled like a cat in heat at the sensation, and he grunted in turn, her body temperature so much higher than normal that it almost felt like the most pleasurable kind of burning around his shaft.

She began to ride him, swaying her hips with the same grace that she’d climbed on top of him with, and while doing it, she continued to change, as if surrendering to lust spurred the transformation onwards. Her breasts swelled a little more until they were just above double or maybe triple Ds, bouncing with utmost eroticism as Kaiden thrust into her. Her face, though increasingly animalistic with whiskers sprouting forth from her cheeks, was awash with pleasure, a strange hybrid of human and animal lust and all the more intense for it. She stared down at him with almost predatory focus, and her pupils dilated as she sped up her pace.

Kaiden was only slightly less animalistic as his own instincts took over. His stronger hands grabbed Mary’s hips and began to bounce her on his lap, effortlessly enabled by his enhanced muscles. He certainly didn’t question anything, even though it felt like an erotic dream. Her silken inner muscles squeezed around him with such intensity that he almost saw stars, and the sheer hunger with which she rode him made sure that he wouldn’t last long. But cats never did last long. Instead, they fucked again and again until their heats were over, and Kaiden was already fantasizing of that as he careened towards his climax.

The cat part had been a little unexpected. Maybe Mary had accidentally mixed up her pills with Mr. Whiskers', but he couldn’t care less about why it had happened; it was hot as hell, and he was already near the point of bursting. And yet, his oversexed wife was the first to cum. She arched her back, yowling with pleasure, and there it was: that irresistible milking, only stronger and more demanding as Mary climaxed harder than she ever had before, her juices squirting out over Kaiden’s pistoning cock. And he had no hope of resisting.

With a half-primal growl of his own, he pulled the thrashing cat down onto his cock, to the very base, with his tightened balls nestled against her body, and then gave into the pleasure. Kaiden erupted into his wife with ropes of silvery white, and it felt like her body was squeezing his seed out of him. His eyes teared up, all muscles tensing in rhythm as he unloaded into her, filling her to the very brim with each ecstatic pulse of his shaft. He came far harder and more than usual, to the point that the backwash soaked his own crotch too, his virility kicked into overdrive by the medicines.

But eventually it ended and he slumped back, with Mary bonelessly lying on top of him, purring quietly.

“All over that depression, then?” Kaiden asked, after a moment of catching his breath.

“Yeah. I feel amazing,” she replied. “Might not be able to go outside like this though.”

“Oh, don’t worry, you can be my housecat,” Kaiden replied playfully. “I’m sure Genron will help convince your boss that you need to work from home.”

They were quite likely to, at least as long as the experiments were useful for them. Then again, neither Kaiden nor Mary were exactly following their regimens, but there was a reason that Genron had made all the experimental pills identical. The few laws that still remained prevented them from intentionally studying the effects of mixing medications, but if their carefully observed test subjects did it on their own, they could hardly be considered liable, could they?

“Or we just enjoy this for a bit and then see if we can fix it,” she huffed, and Kaiden found himself agreeing. Even if it meant just a few weeks of amazing sex, it was totally worth it.

Mary was left panting after their amazing session, Kaiden’s thick cum still oozing from her flushed, pink pussy. She purred quietly. Being part-cat wasn’t so bad. Sure, she couldn’t go outside, but she didn’t want to go outside anyway, not with that smog filling the air. Leisurely, she stretched after Kaiden got up, her claws extending and digging into the mattress playfully.

It was kind of a shame that she was the only one to get to feel so good, though, Mary thought, in her physically enhanced but mentally diminished state. Kaiden deserved to be happy too, not just horny. That, and while him being a human was hot and all, she shuddered with excitement as she imagined how her husband would look as an anthropomorphic cat like herself.

She could mix her pills into his. And maybe some of the cat’s, too. The thought made her pussy clench despite her recent climax. It’d be immoral, but it wasn’t as if it had done any damage to her, right?

Well, besides the whole cat thing. But that part was hot. It made the sex they had so much better. And she had a sneaking suspicion that he had already dosed her with his pills, given how strong and energetic – and horny – she felt, which wasn’t a side effect of what she was testing. Mary couldn’t know for sure, of course, but it was pretty likely, and so, wasn’t turnabout fair play?

He could be a big studly cat for her to fuck.

Her hand lazily slipped down over her well-used and rather happy sex. Her clit felt a bit bigger than it had before, which she had noticed with how it rubbed against her panties. Thinking was still hard, but the thought did occur to her; was she growing? That little pleasure-nub had grown from just that, a nub, into something about the size of her fingertip.

What other effects could these miraculous drugs have, she wondered, fighting the urge to just masturbate, and with it, the desire to dose up her husband too. It wasn’t right, but it felt right. What if she just did it once? _ Again, that warm, damp _clench. She was getting entirely too excited by the idea and knew that she should stop herself, but by now, it was increasingly difficult to even try to control herself. And if that was true for her, then it'd also be true for Kaiden if he got dosed with her “antidepressants” that seemed to erode inhibitions and logical thinking.

Don’t do it, Mary. Just be a cat yourself, she tried telling herself. But that’d be boring. She wanted to yowl in heat as her feline mate pounded her, as he bred her, and there was another, far more unfamiliar and almost alien urge developing in the back of her mind, too. She wanted to fuck him, too. Suddenly her growing, swelling clit made perfect sense.

Mary stared at her pills. If she took another dose, doubling it again – she thought, at least, having lost track of just how many she had already taken – maybe she’d be able to. Maybe she’d grow a cock. But if she took more, there was no way she could resist drugging Kaiden too; it was already so damn difficult to fight those ill-guided fantasies that left her dripping wet.

She slid a finger into her cum-drenched sex, already beginning to rub herself again despite just having cum. The pills felt oddly heavy in her hand as Mary fondled her clit, fantasizing of it growing, maybe even into a big, fat cock that she could slide into… gods, if Kaiden somehow grew a pussy they could just fuck each other senseless all night. That was what that itchy urge in her mind was; she wanted to be on top. With this many clearly transformative drugs it might actually happen! Her fingers moved faster, three of them pumping into the mess inside her and curling against her inner walls.

Her hand, the one with the damned pills in it, went to her mouth almost instinctively while the other brought her closer and closer to orgasm. The more she tweaked her clit, the more she fingerfucked herself, the more she wanted to swallow them. The idea seemed better with each moment. Arousal always made terrible ideas feel so much more appealing, and she was no different, and so, just as she was teetering on the edge of climax, she put the pills in her mouth. Just holding them there felt erotic, and she didn’t have to swallow them unless she wanted to. It was all play. She wasn’t going to do it, Mary told herself.

But then her orgasm hit. She almost curled up at how intense it felt, those waves of pleasure washing over her. Mary even let out a yowl, and in the throes of her orgasm the pills fell into her throat and she swallowed instinctively. It took her a few ecstasy-filled moments to realize what had happened, and when she did, it intensified her orgasm to the point that she gushed over her fur-clad hand, soaking it utterly into her juices, her tail spasmodically thwapping against the mattress.

Maybe she would do it. Just this once. Just to see what’d happen, and then never again.

Day Five

Kaiden thought nothing of the food they ate. Strongly flavored macaroni and cheese, as they’d grown accustomed to during their time without much money to spare. Sure, it had crunchy bits as always, but that was part of the appeal, and so the thought that his feline partner might have crushed up some of the pills to add to his portion didn’t even occur to him, just as him double-dosing her hadn’t occurred to Mary. After all, she had always been the more responsible one out of the two, and besides, Kaiden was so hungry with all those big muscles needing nutrition that he ate too fast for the suspicion to even have a chance to form.

He thought about something he had found out when researching Mary’s condition the other day. Such changes were reversible with some genetic manipulation, in theory. But any such therapy was strictly banned on pregnant people due to all those new laws. In other words, he’d have to be careful not to knock her up, and he told her as much while eating.

“Yeah,” she responded, barely listening to him, or at least not comprehending the words he said. “Probably shouldn’t be a problem.”

He didn’t even notice how Mary stared at him, her slit pupils dilated into almost perfect roundness with anticipation and excitement as she returned the favor that she was sure he had done to her before. The dose was so big that halfway through the meal, his chest was already beginning to plump out into a more feminine shape, with a fuzzy growth of black fur on his skin, and he didn’t notice either, thanks to the same sensual fog that had engulfed Mary slowly settling in.

In fact, he found himself enjoying it with each crushed and dissolved pill that he ate. He felt so very good. Not quite as clear and vigorous as he had felt before, but aglow, throughout his whole body. Mary stared at those growing breasts and licked her lips, but he was more focused on how full his boxers felt with his cock responding eagerly to the drugs, growing both hard and bigger yet, to an outright obscene size and clouding his mind further.

He didn’t really know where those feelings came from, but it all felt so very wonderful. Slowly, his mind became entirely focused on sex, on fucking Mary’s brains out in a frenzy of lust. By the time they’d finished eating and gotten the dishes done, it was hitting him hard.

Suddenly, he felt dizzy. He stumbled towards the living room, only barely managing to get there and brace against the couch before his legs gave out and he collapsed chest-first onto it. There was a pain, or rather, an ache as a pair of rapidly growing breasts squashed against the pillows. His legs didn’t respond, as if paralyzed, but he could feel the bones and joins shift and move as his heels pulled up into a digitigrade posture.

He had trusted Mary. But on the other hand, there was a sudden surge of pleasure just behind his balls. An overwhelming wave of joy that left him shivering, unable to think whatsoever as a trickle of wetness escaped from a pair of forming lips.

Mary watched, her mouth dry with anticipation. She had taken so much of the medicine that her mind, too, was all but blanked out by pure lust, her juices running down her furred thighs as she watched Kaiden slowly change. And she was growing too; her clit was about the length of a finger, and it grew with each stroke of her soft hand, twitching as it slowly started to resemble a real cock. With it, that desire to fuck Kaiden intensified. And to get fucked by him, too, each need as intense as the other.

She knelt next to him, running a clawed hand down his increasingly furry back, and Kaiden growled, his voice sounding unfamiliar at first as both his throat and mouth were reshaped by the medicine. There were too many sensations all at once to consider what any of them meant, from the aching weight on his chest where his new breasts were growing to an impressive size, to that needy, wet heat between his legs. Or the fur replacing what little body hair he had, leaving him covered in black, feline fuzz, just like Mary was.

Beyond any of that, he felt so deeply carnal, like the entire world was just pleasure, the feelings threatening to swallow him whole as he squirmed, his muscles swelling and flexing. Mary was already on top of him, grinding her almost fully grown cock against his soft asscheeks. Oh, he was still far bigger than her, but that didn’t matter. It wasn’t a competition, only an exhibition of two changed and former humans melting into absolute, dissolute, debauched pleasure together.

She held out another handful of pills for Kaiden, and he ate them from her hand, too far gone to question the act as his raspy tongue scooped each one up in turn. Her cock immediately twitched as it grew another pleasurable, beautiful inch. His breasts swelled a little further, growing an entire cup size. But more than anything, there was a warm sensation of painless cramping in his lower belly, but of course, with all of it being new to him, Kaiden couldn’t know that he was growing a womb, rendered fertile by the second dose, and soon he was already in full heat, squirming and thrashing. He ended up on his back, legs spread and that new, leaking, feminine sex bared for his mate.

She was on top of him in an instant with a lusty growl, pretend-pinning the much stronger male down by the wrists as she clumsily thrust her new cock under his balls and into that wet, warm, blissful place. He clenched around her, and she moaned out again. The entire world stopped mattering; the only meaningful thing that existed was his wonderful pussy, threatening to milk everything out of her in heated desperation. Her own clenched, but that could wait; right now, her cock demanded her full attention and obedience.

“Now we can both be cats in heat,” she teased him, leaning down to lick her husband’s furred neck with her raspy tongue before kissing him, still tasting the chalky flavor of the pills on his lips and scooping up as much as she could for herself.

She was only teasing about the heat, but unbeknownst to them, they were both rapidly going into it, their changed bodies primed and ready for reproduction, and their minds very much not in a place where they could prevent it from happening. Or even consider the possible consequences that emptying her growing, plumping balls into Kaiden’s new and entirely too eager pussy could have.

There was a little moment of hesitation, but it was quickly gone from her mind as the pill-crumbs melted in her mouth and soaked into her bloodstream, turning into more excitement until she was simply utterly unable to resist her urges, or the vice-like yet sensual squeezing around her demanding, imposing cock.

Unfamiliar as she was with her new anatomy, she fucked Kaiden’s fertile new sex clumsily but with total, passionate abandon, his growing wetness around egging her on further. Kaiden had only the faintest notion of what was even happening, the overdose of pills having completely blanked out his thoughts, but he was perfectly aware of that wonderful hardness rutting into him, and the pleasure of it seemed to radiate through his entire body until he was bucking back into her thrusts.

It was a strange sensation, feeling her shaft throb and buck inside him, but it was so pleasurable as it rubbed against every inner bundle of nerves that Kaiden could only wriggle beneath her, the joy sapping the strength from his muscles. His own cock. hard as steel, bounced with each thrust, and so did his breasts, rubbing against Mary’s own and making them both moan, whimper, and yowl.

But as they had already learned, cats didn't last long. In a span of only a few minutes, Mary’s thrusts reached a rapid cadence, slamming into Kaiden as quickly as she could as she chased that hedonistic, all-consuming high of her first “male” orgasm, already threatening to boil over in her loins. She didn’t care about any risks. She wasn’t even aware of the risks, only that she needed to cum, and she needed to cum deep into that clutching pussy to the point her muscles were spasming to drive herself deeper.

It was another new, yet deeply fulfilling, feeling for Kaiden. Mary’s cock pulsed hard inside him, and then, there was a muted feeling of tickling heat as the first thick rope of cum – far more potent than it had any right to be, thanks to Kaiden’s own medicine – erupted against his new cervix. That was quickly followed by the same feeling again and again, in slick, rhythmic succession that had him squirming, not quite being able to connect the dots but subconsciously enjoying the feeling of being well and truly inseminated for the first time as his changed body eagerly took in everything that Mary had to offer.

That initial strangeness was followed by a sudden wave of deep sexual fulfilment, strong enough that it made his pussy clench hard, his legs trembling as an entirely unfamiliar but glorious kind of orgasm suddenly rushed through him. No cum erupted from his own cock, but instead it felt like his entire body was that wet, white-hot orifice under his balls, and like every muscle in his body clenched at once along with that fluttering in his lower belly, those inner muscles contracting to suck Mary’s potent cum deeper into himself.

Mary kept grinding into him after her orgasm had ended, so transfixed by the feeling of breeding someone that it kept her hips moving on their own for a few moments longer, before relaxation overcame her and she pulled out, rolling over and stretching leisurely. She suddenly incredibly felt clear-headed, as most people with cocks typically did after emptying their balls, and so, thoughts about the consequences to their revelry began to slowly filter in through the happy fog. She had just cum inside Kaiden. That felt like a thing she shouldn’t have done. Wasn’t there a chance that he’d-

-Kaiden pounced her in turn, pulling her hindquarters up with a lusty growl. Before she could protest or even react, his own cock was inside her, the massive size of it stretching her to the very limit.

“K-Kaiden, f-fuck,” she mewled. “W-what if we’re both…”

He didn’t care, clamping a hand over Mary’s snout as he began to fuck her, and this time, he fucked her hard. He’d only had a “female” orgasm after all, and even as Mary’s cum dripped from his filled pussy, he needed relief. The drugs had left him so hypercharged, so mind-numbingly horny that he barely even, in that heated moment, recognized his wife as more than a warm, fertile hole that he fully intended to breed.

Being stronger than her, he easily held the struggling, squirming Mary in place as he rutted her, in turn racing towards the inevitable climax of the descent into mindless debauchery. But of course, in the end, she was just as affected, and the resistance quickly melted out of her as she was fucked, the pleasure once again quickly burning reason to ashes. It didn’t take long before she was yowling with joy once again as she squeezed around Kaiden’s cock, her body cheering him on, wanting and thirsting for a load of fresh, belly-swelling seed of her own.

His strong hands mauled her swollen breasts, his claws raked over her shapely body, and his cock ravaged her receptive pussy, fucking her until she was nothing but a limp, shivering form of pure pleasure, rocked to-and-fro by his thrusts. And then he came again, filling his helpless feline wife with great spurts of his seed in turn, only this time, those eager little swimmers would find far more fertile ground, with both of their bodies primed to the maximum by the medicine. She cried out in pleasure, cumming again and again until she could barely remember who, where, or when she was, the roaring conflagration of ecstasy consuming every last fragment of her mind until Kaiden’s hips finally stopped moving.

They were left dazed, both leaking with each other’s cum, staring at each other with lust-glazed eyes before they ended up cuddled together on the sofa, slowly regaining at least a little of their capacity for thought as the day or night – they didn’t know what time it was in the slightest, having been so caught up in their revelry for what felt like hours – dragged on.

Mary was the first to speak.

“Just… amazing,” she huffed, her voice hoarse from all the moaning.

“Y-yeah, but, oh man, this is gonna be kinda hard to explain,” Kaiden replied.

A few more moments of stillness followed, the cats considering their actions as best they could. “What if I’m- what if we’re pregnant?” Mary finally asked, her thoughts naturally focused a little more on that particular outcome.

Kaiden couldn’t quite formulate a response in his sluggish head. All he knew was that everything that had happened had felt amazing, and he had absolutely no regrets at all. In fact, both his cock and pussy were already tingling for another round, as expected, their changed bodies wanting to make certain what might otherwise be left to chance.

He grabbed a handful of the pills that had fallen onto the floor in the middle of their debauchery and offered them to Mary. She hesitated, but only for a moment, before eating them from his hand, groaning as her breasts quickly responded by growing, her pussy growing wetter, and then, in a once again intensified haze of pleasure, she found himself quickly straddling him for more. Why resist it, it’s gonna happen anyway, was her last thought before pleasure washed it all away again.

Of course, although neither Kaiden nor Mary could remember that little warning he had given her about genetic manipulation being forbidden for those pregnant or about to get pregnant. With both of them ensuring each other’s pregnancies, it’d be nearly impossible to get changed back, making that repeated mating far more fateful than it seemed to their lust-struck minds. It was a reality they’d confront only far, far later.

By the end of the night, both newly-minted cats were well and truly pregnant, having filled each other with extremely virile and potent seed over and over again each time they mated. Not that they cared, feeding each other excessive amounts of their medicine to spur another long fuck-session until every inch of their bodies were aching, their pussies loose and stretched, and their cocks in turn almost red-raw from the constant rutting. It was a pleasant ache though, subdued by the warm, satisfied, yet endlessly horny glow that had fully engulfed them both. Perhaps it wasn’t exactly what they had intended when they started the trials, but for the first time in ages, both Mary and Kaiden were happy and filled with the energy required to get somewhere in life.

Well, after their heats subsided, they would be. It wasn’t an instant process, after all, as even though they had unwittingly successfully fertilized each other, it’d take a few more days of fucking each other like animals before their bodies recognized the triumph of their instinctive, carnal nature. And maybe that wonderful state would only remain until their bellies were so swollen that they’d struggle to get anywhere. But for a few months, everything would be deeply and utterly perfect.

And Mr. Whiskers? He was all too happy to have two enormous cats to cuddle all day long, caring little about what else they got up to as long as he got his pets and snacks.